Table 3 Rcts included in the meta-analysis of cortex
From: Effect of cannabinoids on glutamate levels in the human brain: a systematic review and meta-analysis
Article | Imaging Modality and Parameters | OUTCOMES | REPORTED CONCLUSIONS | |||
|---|---|---|---|---|---|---|
Glx | Glu | Glx/Cre | Glu/Cre | |||
Colizzi et al. 2020 | 1H-MRS 3 T Voxel: ACC (20 × 20x20 mm3) PRESS spectra analysed using LCModel v6.3 - 1L |
|
|
| Â | THC did not affect glutamate levels (Glx, Glu, Glx/Cre) in the ACC |
Mason et al. 2019 | 1H-MRS 7 T Voxel: ACC (25 × 20x17 mm3) STEAM spectra analysed using LCModel v6.3 - 1H |  |  |  |
| THC did not affect Glu/Cre in the ACC |
Pretzsch et al. 2019a | 1H-MRS 3 T Voxel: DMPFC (25 × 40x30 mm3) MEGA-PRESS spectra analysed using LCModel v6.3 - 1L |
| Â | Â | Â | CBD decreased Glx level in the dmpfc |
Pretzsch et al. 2019b | 1H-MRS 3 T Voxel: DMPFC Midline (25 × 40x30 mm3) MEGA-PRESS spectra analysed using LCModel v6.3 - 1L |
| Â | Â | Â | CBDV has no effect on Glx in the dmpfc |
Van boxel et al. 2023 | 1H-MRS 3 T Voxel:Pre-forntal cortex (40 × 30x20 mm3) MEGA-PRESS spectra analysed using LCModel V6.3 - 0 A |
|
| Â | Â | CBD did not significantly affect glutamate levels (Glx,Glu) in the prefrontal cortex |
