Table 2 Characteristics of observational studies
From: Effect of cannabinoids on glutamate levels in the human brain: a systematic review and meta-analysis
Article | Study Design | Intervention | Dose | Population | Sample Size | Duration of Treatment (Tx) | Frequency of Tx | Delivery of Tx |
|---|---|---|---|---|---|---|---|---|
Bernier et al. 2016 | CS | Cannabis* | nd | Schizophrenic pts, hx of cannabis taking > 1 year vs healthy controls | 74 | nd | nd | nd |
Blest-Hopley et al. 2020 | CS | Cannabis* | nd | Cannabis users (CU) versus non-users (NU) | 43 | 2 years prior study participation | At least 4Â days/wk for the past | nd |
Chang et al. 2006 | CS | Cannabis* | nd | HIV CU vs HIV NU, and Non- HIV CU and NU | HIV 42 Non-HIV 54 | 2.1 years | At least taking cannabis 19 days per month | nd |
Muetzel et al. 2013 | CS | Cannabis* | nd | Adolescent CU vs NU | 48 | nd | At least 5 × per week for at least one year | nd |
Newman et al. 2019 | CS | Cannabis* | nd | Adolescent CU vs Adolescent NU | 48 (25 CU 23 NU) | nd | nd | nd |
Prescot et al. 2011 | CS | Cannabis* | nd | Adolescent CU vs Adolescent NU | 34 | Ave age of first use: 15 years old | 1367 total no of cannabis smokes | Inh |
Prescot et al. 2013 | CS | Cannabis* | nd | Adolescent CU vs Adolescent NU | 29 (16 CU vs 13 NU) | Ave age of first use: 15 years old | 1124 total no of cannabis smokes | Inh |
Rigucci et al. 2018 | CS | Cannabis* | nd | Early Psychosis (EP) CU vs EP NU and HC | 68 EP CU- 18 EP NU- 17 HC- 33 | Ave age of first use: 17 years old | Either daily or weekly cannabis use | nd |
Sami et al. 2020 | CS | Cannabis* | nd | EP history of CU, EP with minimal CU, and HC with CU and HC w/o CU | 29 EPC 25 EPMC 16 HCC 12HCMC | Ave age of first use: 16 years old | nd | nd |
Subramaniam et al. 2022 | CS | Cannabis* | nd | Adolescent CU vs NU | 39 | Ave age of regular use: 16.74 years old (mean) | At least 100 × in the last 12 months prior enrolment | nd |