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Table 4 CBD may alter the regulation of sex hormones

From: Beyond the hype: a comprehensive exploration of CBD’s biological impacts and mechanisms of action

Enzyme

Full enzyme name

Interaction

Reference(s)

Aromatase

Estrogen synthetase/synthase

Antagonism

Almada et al. 2020)

17OHP/CYP17A1

Progesterone 17-hydroxylase

Antagonism

Watanabe et al. 2005)

CYP3A7

Cytochrome P450 3A7

Inhibition

Yamaori et al. 2011)

CYP1B1

Cytochrome P450 1B1

Antagonism

Yamaori et al. 2010)