Fig. 6

Effects of the synthetic cannabinoid MMB-2201 treatment on mRNA expression in endothelial cells. The results of qRT-PCR showed the upregulation of several angiogenic genes, including VEGF, ANG-1, and ANG-2, at different concentrations of MMB-2201. Data are presented as mean ± SEM (n = 3). (*) indicates p < 0.05. (****) indicates p < 0.0001