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Fig. 4 | Journal of Cannabis Research

Fig. 4

From: Evaluation of the metabolic activity, angiogenic impacts, and GSK-3β signaling of the synthetic cannabinoid MMB-2201 on human cerebral microvascular endothelial cells

Fig. 4

The synthetic cannabinoid MMB-2201 promoted the migration rate of endothelial cells. A wound was introduced in the confluent endothelial monolayer in 12-well plates. Different concentrations of MMB-2201 were incubated with the cells for 24 h. (A) Microscopic images of migrated HBEC-5i cells were captured at baseline (Zero time) and after 24 h. (B) Quantitative analysis of the migration data revealed a significant increase in cell migration in cells treated with different concentrations of MMB-2201. Data are presented as mean ± SEM (n = 3). (***) indicates p < 0.001. (****) indicates p < 0.0001

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