Fig. 5
From: Selected cannabis cultivars modulate glial activation: in vitro and in vivo studies
TNFα and IFNγ secretion in splenocytes from EAE mice treated with extracts of 2 cannabis cultivars. At the completion of the EAE studies, splenocytes were harvested from mice untreated or treated with MOG35-55 (MOG) injected with vehicle (Veh) CN2 or CN4 cannabis cultivars. The medium was collected after 48 hours and tested for IFNγ (A) and TNFα levels (B) by ELISA. Presented results are means±SEM. Statistical significance was determined by one-way ANOVA and Tukey-Kramer Multiple Comparison Post Test - *** p <0.001 vs. control, ** p < 0.01 vs. control, * p <0.05 vs. control, ^^^ p <0.001 vs. MOG, ^ p <0.05 vs. MOG, ## p <0.001 vs. CN4 # p <0.05 vs. CN4, #. n = 5-15