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Fig. 2 | Journal of Cannabis Research

Fig. 2

From: Propylene glycol and Kolliphor as solvents for systemic delivery of cannabinoids via intraperitoneal and subcutaneous routes in preclinical studies: a comparative technical note

Fig. 2

H&E staining of skin samples from treated rats. A Saline. B Propylene glycol. C CBD only. D THC only. E CBD + THC. A Saline: normal skin, no significant inflammation. B Propylene glycol: extensive superficial and deep neutrophilic inflammation with associated granulation tissue. C CBD only: ranging from granulation tissue and palisading neutrophilic abscess with necrobiosis, debris, and surface bacterial infection to ulcer and full-thickness cutaneous necrosis. D THC only: granulation tissue and palisading neutrophilic abscess with necrobiosis and debris. E CBD + THC: granulation tissue and palisading neutrophilic abscess with necrobiosis and debris

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Journal of Cannabis Research

ISSN: 2522-5782