|  | 18–29 years ( n  = 53) (M ± SD) | 30–39 years ( n  = 88) (M ± SD) | 40 + years ( n  = 41) (M ± SD) | ANOVA or χ 2 | p -value |
---|---|---|---|---|---|---|
Gender | Â | 33 females and 20 males | 56 females and 32 males | 25 females and 16 males | Â | Â |
Number of logged sessions | Â | 196 | 558 | 251 | Â | Â |
Pre-medication anxiety score |  | 6.43 (± 1.99) | 5.58 (± 2.40) * | 6.05 (± 1.90) | F = 12.10 | p < 0.001 |
Post-medication anxiety score |  | 2.46 (± 1.94) | 1.98 (± 2.03) * | 2.70 (± 1.79) | F = 13.28 | p < 0.001 |
Average efficacy (%) |  | 50.2 (± 25.4) | 52.0 (± 25.0) | 44.8 (± 19.6)^ | F = 9.14 | p < 0.001 |
Optimal dose (number of inhalations) |  | 4–6 | 5–7, 11–13 | 4–5 |  |  |
Percent reporting positive emotives (%) |  | 85.7# | 98.5% | 96.6% | χ2 = 7.81 | p = 0.02 |
 | Top 1 specific negative emotive (%) | Relaxed (62.9%) | Relaxed (86.8%) | Relaxed (82.8%) | χ2 = 8.35 | p = 0.02 |
Top 2 specific negative emotive (%) | Comfortable (51.4) | Comfortable (57.4) | Comfortable (65.5) | χ2 = 1.29 | p = 0.52 | |
Top 3 specific negative emotive (%) | Happy (40.0) | Happy (45.6) Light (39.7) | Happy (41.4) Light (48.3) | Happy χ2 = 0.34 Light χ2 = 3.63 | Happy p = 0.84 Light p = 0.16 | |
Number of different positive side effects selected (out of 17) | Â | 17 | 17 | 16 | Â | Â |
Average number reported positive emotives (M ± SD) |  | 4.3 ± 3.0 | 4.5 ± 2.9 | 4.4 ± 2.6 | F = 0.09 | p = 0.92 |
Percent reporting negative emotives (%) |  | 22.9 | 7.4 | 10.34 | χ2 = 5.33 | p = 0.07 |
 | Top 1 specific negative emotive (%) | Headache (11.4) | Anxious (5.9) | Anxious (10.3) | Anxious χ2 = 0.65 Headache χ2 = 7.75 | Anxious p = 0.72 Headache p = 0.02 |
Top 2 specific negative emotive (%) | Anxious (8.6% | Racing Heart (4.4) | Dizzy (3.5) | Dizzy χ2 = 1.79 | Dizzy p = 0.41 | |
Top 3 specific negative emotive (%) | Dizzy (8.6) Nauseous (8.6) Racing Heart (2.9) | Dizzy (2.9) Headache (1.5) Nauseous (1.5) | Paranoid (3.5) Nauseous (0) Racing Heart (0) | Paranoid χ2 = 1.44 Nauseous χ2 = 5.13 Racing Heart χ2 = 1.35 | Paranoid p = 0.49 Nauseous p = 0.08 Racing heart p = 0.51 | |
Number of different negative side effects selected (out of 6) | Â | 6 | 6 | 3 | Â | Â |
Average number of reported negative emotives (M ± SD) |  | 2 ± 1.4 | 2.4 ± 1.5 | 1.6 ± 1.1 | F = 0.27 | p = 0.77 |
Percent reporting neutral emotives (%) |  | 60.0 | 60.3 | 72.4 | χ2 = 1.45 | p = 0.48 |
 | Top 1 specific neutral emotive (%) | Thirsty (42.9) | Thirsty (32.4) | Thirsty (37.9) | χ2 = 1.14 | p = 0.57 |
Top 2 specific neutral emotive (%) | Hungry (28.6) | Sleepy (26.5) | Sleepy (37.9) | Sleepy χ2 = 1.30 | p = 0.52 | |
Top 3 specific neutral emotive (%) | Sleepy (28.6) Couchlocked (22.9) | Hungry (20.6) Couchlocked (14.7) | Hungry (24.1) Couchlocked (0) | Hungry χ2 = 0.83 Couchlocked χ2 = 7.17 | Hungry p = 0.66 Couchlocked p = 0.03 | |
Number of different neutral side effects selected (out of 12) | Â | 10 | 11 | 10 | Â | Â |
Average number of reported neutral emotives (M ± SD) |  | 3.4 ± 1.9** | 2.3 ± 1.7 | 2.1 ± 1.5 | F = 3.43 | p = 0.04 |