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Table 6 Anxiolytic effects and emotives of cannabis consumption as a function of age. The asterisk denotes p < 0.05 between 30 and 39 years and both other age groups, ^ denotes p < 0.05 between 40 + and both other age groups and # denotes p < 0.05 between 18–29 years and both other age groups. Three participants who logged 23 sessions were not included in this table as they did not report their age. One female participant is included in both the 30–39 years and 40 + years as she logged sessions as a 39- and 40-year-old

From: Naturalistic examination of the anxiolytic effects of medical cannabis and associated gender and age differences in a Canadian cohort

  

18–29 years ( n  = 53)

(M ± SD)

30–39 years ( n  = 88)

(M ± SD)

40 + years ( n  = 41)

(M ± SD)

ANOVA or χ 2

p -value

Gender

 

33 females and 20 males

56 females and 32 males

25 females and 16 males

  

Number of logged sessions

 

196

558

251

  

Pre-medication anxiety score

 

6.43 (± 1.99)

5.58 (± 2.40) *

6.05 (± 1.90)

F = 12.10

p < 0.001

Post-medication anxiety score

 

2.46 (± 1.94)

1.98 (± 2.03) *

2.70 (± 1.79)

F = 13.28

p < 0.001

Average efficacy (%)

 

50.2 (± 25.4)

52.0 (± 25.0)

44.8 (± 19.6)^

F = 9.14

p < 0.001

Optimal dose (number of inhalations)

 

4–6

5–7, 11–13

4–5

  

Percent reporting positive emotives (%)

 

85.7#

98.5%

96.6%

χ2 = 7.81

p = 0.02

 

Top 1 specific negative emotive (%)

Relaxed (62.9%)

Relaxed (86.8%)

Relaxed (82.8%)

χ2 = 8.35

p = 0.02

Top 2 specific negative emotive (%)

Comfortable (51.4)

Comfortable (57.4)

Comfortable (65.5)

χ2 = 1.29

p = 0.52

Top 3 specific negative emotive (%)

Happy (40.0)

Happy (45.6)

Light (39.7)

Happy (41.4)

Light (48.3)

Happy χ2 = 0.34

Light χ2 = 3.63

Happy p = 0.84

Light p = 0.16

Number of different positive side effects selected (out of 17)

 

17

17

16

  

Average number reported positive emotives (M ± SD)

 

4.3 ± 3.0

4.5 ± 2.9

4.4 ± 2.6

F = 0.09

p = 0.92

Percent reporting negative emotives (%)

 

22.9

7.4

10.34

χ2 = 5.33

p = 0.07

 

Top 1 specific negative emotive (%)

Headache (11.4)

Anxious (5.9)

Anxious (10.3)

Anxious χ2 = 0.65

Headache χ2 = 7.75

Anxious p = 0.72

Headache p = 0.02

Top 2 specific negative emotive (%)

Anxious (8.6%

Racing Heart (4.4)

Dizzy (3.5)

Dizzy χ2 = 1.79

Dizzy p = 0.41

Top 3 specific negative emotive (%)

Dizzy (8.6)

Nauseous (8.6)

Racing Heart (2.9)

Dizzy (2.9)

Headache (1.5)

Nauseous (1.5)

Paranoid (3.5)

Nauseous (0)

Racing Heart (0)

Paranoid χ2 = 1.44

Nauseous χ2 = 5.13

Racing Heart χ2 = 1.35

Paranoid p = 0.49

Nauseous p = 0.08

Racing heart p = 0.51

Number of different negative side effects selected (out of 6)

 

6

6

3

  

Average number of reported negative emotives (M ± SD)

 

2 ± 1.4

2.4 ± 1.5

1.6 ± 1.1

F = 0.27

p = 0.77

Percent reporting neutral emotives (%)

 

60.0

60.3

72.4

χ2 = 1.45

p = 0.48

 

Top 1 specific neutral emotive (%)

Thirsty (42.9)

Thirsty (32.4)

Thirsty (37.9)

χ2 = 1.14

p = 0.57

Top 2 specific neutral emotive (%)

Hungry (28.6)

Sleepy (26.5)

Sleepy (37.9)

Sleepy χ2 = 1.30

p = 0.52

Top 3 specific neutral emotive (%)

Sleepy (28.6)

Couchlocked (22.9)

Hungry (20.6)

Couchlocked (14.7)

Hungry (24.1)

Couchlocked (0)

Hungry χ2 = 0.83

Couchlocked χ2 = 7.17

Hungry p = 0.66

Couchlocked p = 0.03

Number of different neutral side effects selected (out of 12)

 

10

11

10

  

Average number of reported neutral emotives (M ± SD)

 

3.4 ± 1.9**

2.3 ± 1.7

2.1 ± 1.5

F = 3.43

p = 0.04