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Table 5 Anxiolytic effects and emotives of consuming a THC sativa cultivar as a function of gender. The asterisk denotes p < 0.05 for the comparison between males and females. One participant logged 5 sessions and reported their gender as “unknown.” Their data was included in the total but not in either the male or female categories

From: Naturalistic examination of the anxiolytic effects of medical cannabis and associated gender and age differences in a Canadian cohort

  

Total ( n  = 70)

Male ( n  = 33)

Female ( n  = 36)

t or χ 2

p -value

Number of logged sessions

 

315

173

137

  

Pre-medication anxiety score

 

6.24 (± 1.92)

6.27 (± 1.83)

6.20 (± 2.02)

t = -0.31

p = 0.76

Post-medication anxiety score

 

2.30 (± 1.75)

2.37 (± 1.57)

2.20 (± 1.95)

t = -0.808

p = 0.42

Average efficacy (M ± SD; %)

 

51.72 (± 21.68)

50.66 (± 21.53)

53.06 (± 21.86)

t = 0.964

p = 0.34

Optimal dose (number of inhalations)

 

4–7

4–5

6–7

  

Percent reporting positive emotives (%)

 

97.9

100

96.0

χ2 = 0.94

p = 0.33

 

Top 1 specific positive emotive (%)

Relaxed (66.7)

Relaxed (73.9)

Relaxed (60.0)

χ2 = 1.04

p = 0.31

Top 2 specific positive emotive (%)

Comfortable (62.5)

Comfortable (69.6)

Comfortable (56.0)

χ2 = 0.94

p = 0.33

Top 3 specific positive emotive (%)

Happy (52.1)

Happy (56.5)

Happy (48.0)

χ2 = 0.35

p = 0.55

Number of different positive side effects selected (out of 17)

 

17

17

16

  

Average number reported positive emotives (M ± SD)

 

4.8 ± 2.9

5 ± 2.8

4.6 ± 2.9

t = -0.60

p = 0.55

Percent reporting negative emotives (%)

 

14.5

8.7

20

χ2 = 1.23

p = 0.27

 

Top 1 specific negative emotive (%)

Anxious (10.4)

Anxious (8.7)

Anxious (12.0)

χ2 = 0.01

p = 0.91

Top 2 specific negative emotive (%)

Racing heart (6.3)

Racing heart (4.3)

Racing heart (8.0)

χ2 = 0.27

p = 0.6

Top 3 specific negative emotive (%)

Dizzy (2.1)

Headache (2.1)

Nauseous (2.1) Paranoid (2.1)

Nauseous (4.3 Paranoid (4.3)

Dizzy (0)

Headache (0)

Dizzy (4.0)

Headache (4.0) Nauseous (0) Paranoid (0)

Dizzy χ2 = 0.94

Headache χ2 = 0.94

Nauseous χ2 = 1.11

Paranoid χ2 = 1.11

Dizzy p = 0.33

Headache p = 0.33

Nauseous p = 0.29

Paranoid p = 0.29

Number of different negative side effects selected (out of 6)

 

6

4

4

  

Average number of reported negative emotives (M ± SD)

 

1.7 ± 1.1

2.5 ± 2.1

1.4 ± 0.5

t = -1.23

p = 0.27

Percent reporting neutral emotives (%)

 

58.3

60.9

56

χ2 = 0.12

p = 0.73

 

Top 1 specific negative emotive (%)

Thirsty (35.4)

Thirsty (34.8)

Thirsty (36.0)

χ2 = 0.01

p = 0.93

Top 2 specific negative emotive (%)

Hungry (25.0)

Hungry (26.1)

Hungry (24.0)

χ2 = 0.03

p = 0.87

Top 3 specific negative emotive (%)

Restless (14.6)

Sleep (14.6)

Restless (17.4)

Sleepy (8.7)

Sleepy (20.0)

Restless (12.0)

Restless χ2 = 0.28

Sleepy χ2 = 1.30

Restless p = 0.6

Sleepy p = 0.27

Number of different neutral side effects selected (out of 12)

 

11

11

10

  

Average number of reported neutral emotives (M ± SD)

 

2.2 ± 1.3

2.2 ± 1.1

2.2 ± 1.6

t = -0.03

p = 0.98