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Table 3 Anxiolytic effects and emotives of consuming a THC indica cultivar as a function of gender. The asterisk denotes p < 0.05 for the comparison between males and females. One participant logged 2 sessions and reported their gender as “unknown.” Their data was included in the total but not in either the male or female categories

From: Naturalistic examination of the anxiolytic effects of medical cannabis and associated gender and age differences in a Canadian cohort

  

Total (n = 93)

Male (n = 30)

Female (n = 62)

t or χ2

p-value

Number of logged sessions

 

344

156

186

  

Pre-medication anxiety score

 

6.65 (± 2.25)

6.01 (± 2.33)*

7.18 (± 2.04)

t = 4.88

p = 0.000002

Post-medication anxiety score

 

2.81 (± 2.15)

1.95 (± 1.43)*

3.53 (± 2.38)

t = 7.584

p < 0.000001

Average efficacy (M ± SD; %)

 

48.33 (± 24.17)

53.18 (± 22.21)*

44.27 (± 25.03)

t = -3.487

p = 0.0006

Optimal dose (number of inhalations)

 

10–11

10–11

10–11

  

Percent reporting positive emotives (%)

 

91.0

100

86.1

χ2 = 3.68

p = 0.06

 

Top 1 specific positive emotive (%)

Relaxed (79.1)

Relaxed (87.5)

Relaxed (74.4)

χ2 = 1.60

p = 0.21

Top 2 specific positive emotive (%)

Comfortable (53.7)

Comfortable (50.0)

Comfortable (55.8)

χ2 = 0.21

p = 0.65

Top 3 specific positive emotive (%)

Happy (35.8)

Happy (41.7)

Light (41.7)

Happy (32.6)

Light (23.3)

Happy χ2 = 0.56,

Light χ2 = 2.49

Happy p = 0.46

Light p = 0.11

Number of different positive side effects selected (out of 17)

 

17

17

16

  

Average number reported positive emotives (M ± SD)

 

3.67 ± 2.24

4.00 ± 2.60

3.46 ± 1.98

t = -0.87

p = 0.39

Percent reporting negative emotives (%)

 

7.5

4.2

9.3

χ2 = 0.588

p = 0.44

 

Top 1 specific negative emotive (%)

Anxious (4.5)

Dizzy (4.2)

Anxious (7.0)

  

Top 2 specific negative emotive (%)

Dizzy (4.5)

NA

Dizzy (4.7)

Dizzy χ2 = 0.01

p = 0.93

Top 3 specific negative emotive (%)

Headache (1.5)

NA

Headache (2.3)

  

Number of different negative side effects selected (out of 6)

 

6

1

6

  

Average number of reported negative emotives (M ± SD)

 

2.00 ± 1.40

Avg = 1

2.25 ± 1.41

NA

 

Percent reporting neutral emotives (%)

 

71.6

70.8

72.1

χ2 = 0.003

p = 0.96

 

Top 1 specific negative emotive (%)

Sleepy (38.8)

Thirsty (45.8)

Sleepy (41.8)

Sleepy χ2 = 0.47

Sleepy p = 0.49

Top 2 specific negative emotive (%)

Thirsty (35.8)

Sleepy (33.3)

Thirsty (39.5)

Thirsty χ2 = 0.25

Thirsty p = 0.62

Top 3 specific negative emotive (%)

Hungry (34.3)

Hungry (29.2)

Hungry (37.2)

Hungry χ2 = 0.21

Hungry p = 0.65

Number of different neutral side effects selected (out of 12)

 

10

9

10

  

Average number of reported neutral emotives (M ± SD)

 

2.33 ± 1.48

2.53 ± 1.77

2.23 ± 1.31

t = -0.62

p = 0.54