Fig. 4

Changes over time of concentrations of Δ⁹THC and metabolites in the A blood, B plasma, C liver, and D urine. Two-way analysis ANOVA (metabolites vs time) was statistically significant for each panel (p=0.05) with metabolites accounting for the greatest percentage of total variance in levels of Δ⁹THC, Δ⁹THC-COOH, and Δ⁹THC-OH