Anti-cancer properties of cannflavin A and potential synergistic effects with gemcitabine, cisplatin, and cannabinoids in bladder cancer

Table 1 Highest and lowest levels of interaction between cannflavin A and gemcitabine and/or cisplatin in T24 cells

Score	CannA (μM)	Cisplatin (μM)	Score	CannA (μM)	Gemcitabine (nM)	Score	CannA (μM)	Gemcitabine (nM): cisplatin (μM)
− 29.53	50	6.25	− 32.39	1.25	25	− 30.87	0.625	62.48:7.81
− 33.77	50	12.5	− 35.04	1.25	12.5	− 32.83	12.5	17.81:0.97
− 35.37	100	50	− 39.66	1.25	6.25	− 36.04	12.5	15.6:1.95
9.72	1.56	0.2	16.96	2.5	50	18.79	6.25	62.48:7.81
13.29	100	0.39	21.35	0.625	50	19.52	25	250:31.25
14.69	25	0.39	32.80	0.625	25	22.54	3.13	250:31.25

A score < − 10 is likely antagonistic (italic); between − 10 and + 10 is likely additive (normal text); > +10 is likely synergistic (bold)

ISSN: 2522-5782