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Fig. 8 | Journal of Cannabis Research

Fig. 8

From: THC and CBD affect metabolic syndrome parameters including microbiome in mice fed high fat-cholesterol diet

Fig. 8

Effect of THC or CBD treatment on CB1 receptor gene expression in the liver of mice fed HFCD. Male C57BL/6J mice aged 7–8 weeks were fed either normal diet (ND, n = 8), high fat + 1%(w/w) cholesterol + 0.5%(w/w) cholate diet (HF-C, n = 8), HFCD containing CBD (2.39 mg/kg) (HF-C CBD, n = 8), HFCD containing THC (2.5 mg/kg) (HF-C THC, n = 8). At the conclusion of the experiment, RNA was isolated from harvested livers and gene levels quantified using qPCR. Values are expressed as relative expression compared to ND (mean ± SEM)

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